DPIA (bisamphetamine; di(beta-phenylisopropyl)amine) appears to degrade in the body to amphetamine (and other products). DPIA is thought to be a psychoactive synthetic by-product formed during the manufacture of amphetamine. The substance is poorly understood and there is little reliable information regarding risks, toxicity, and long-term effects.
DPIA has a blood pressure-increasing effect similar to amphetamine and leads to loss of appetite. In addition, DPIA exhibits a mild stimulant effect, but this is much less pronounced than that of amphetamine.
The toxicity of DPIA is described as moderate with potential for acute or long-term toxic effects.
Each synthesis impurity represents an unknown health risk: the properties hazardous to health have never been scientifically studied and are therefore difficult to estimate. The more different synthesis impurities are contained in a sample, the greater the probability that an impurity with a high adverse health effect is among them. Even a small amount of such an impurity can be harmful. In addition, synthetic impurities are an indication of improper manufacturing/purification. It is also important to add that regular use of amphetamine with synthetic impurities poses a higher health risk than one-time use.