In 2025, the Drug Information Center (DIZ) in Zurich analyzed 690 samples declared as MDMA. Of these, 322 were pills declared as MDMA . Of these, 262 were tested as part of the DIZ’s outpatient drug testing program, and 60 were tested during the nine mobile drug testing events held in the city of Zurich in 2025. In addition, 367 crystalline MDMA samples were submitted for analysis at the DIZ last year. Of these, 308 were tested as part of the outpatient drug testing program at the DIZ, and 59 were tested during the nine mobile drug testing operations.
The detailed 2025 MDMA analysis can be found in the attached report. These are the key findings from 2025:
General
– As in previous years, MDMA remains one of the most commonly tested substances.
– The number of samples containing unexpected pharmacologically active substances increased for both pills and crystalline samples. Compared to the past 10 years, the amount of unexpected pharmacologically active substances is relatively high in both pills and crystalline samples.
MDMA pills
– At 173.7 mg, the MDMA content in MDMA pills is very close to last year’s levels and is in line with the average over the past 10 years.
– 92.2% of all pills tested contain high doses (over 120 mg of MDMA per pill). Nearly one in four of all pills tested even contain extremely high doses (over 200 mg of MDMA per pill).
– 13% of all pills tested contained an unexpected psychoactive ingredient in addition to or in place of MDMA. This represents the highest level in the past 10 years. There were no new unexpected substances; rather, there was an increase in all unexpected substances already known from previous years. The most significant increases were seen in amphetamine, caffeine, and ketamine.
– Unlike the crystalline samples, synthetic cathinones were found only sporadically.
MDMA crystals
– As in previous years, the average MDMA content remains high.
– One in ten samples contained unexpected pharmacologically active substances in addition to or in place of MDMA.
– The number of samples containing synthetic contaminants decreased
– Synthetic cathinones are now the most common unexpected substances found. In most cases, these were mislabeled samples—that is, samples that did not contain any MDMA at all. The synthetic cathinone 4-CMC is the most common unexpected substance found in crystalline MDMA samples.
You can find more information about MDMA on our website here.
The results published here are not representative of the substance market in the city of Zurich.
