Substances / DMT - Changa - Ayahuasca

DMT (N,N-dimethyltryptamine) is a naturally occurring psychedelic found in plants, animals and humans, but is usually sold in extracted form as a crystalline powder.

Changa is a mixture of plants containing DMT (usually crystalline DMT) and herbs for smoking

Ayahuasca is a shamanic herbal potion made from DMT-containing chacruna leaves (Psychotria viridis) and the harmaline-containing ayahuasca liana Banisteriopsis caapi.

5-MeO-DMT is structurally related to DMT and is usually present in crystalline form. The effect is comparable to that of DMT, but 5-MeO-DMT is more potent than DMT and is therefore dosed much lower.

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Effect

With smoked and snorted DMT, the onset of effect is usually perceived as overwhelming in terms of speed and intensity. With all forms of consumption, euphoric feelings can arise as well as an altered, greatly slowed sense of time. Immersion in very bizarre worlds, separation of body and mind, ego dissolution, and a sense of oneness with matter are often experienced. Physical effects include increased blood pressure and pulse, and dilation of the pupils.

Duration

Onset of action
DMT
Smoked: after a few seconds
Swallowed: after 30 - 60 minutes

5-MeO-DMT
smoked: after a few seconds
snorted: after a few minutes

Duration of effect
DMT
smoked: 5 - 20 minutes

Ayahuasca:
1 - 6 hours, but can linger for 1 - 8 hours (!). Higher doses of ayahuasca lead to a prolongation of the effect.

5-MeO-DMT
smoked: 5 - 20 minutes
snorted: 30 - 45 minutes The high usually lingers for 1 - 2 hours.

Dosage

Dosage
DMT
smoked: 15 - 60 mg (only possible in a glass pipe)
snorted: 20 - 50 mg
swallowed: 30 - 150 mg

Changa:
Depending on the actual DMT content.

Ayahuasca:
Dependent on actual DMT content.

5-MeO-DMT
smoked 2 - 15 mg
snorted: 2 - 20 mg
injected 2 - 3 mg

5-MeO-DMT must be dosed very carefully, as even a few milligrams more can cause a very intense and unpleasant effect that can involve psychological and mental problems lasting several weeks.

Appearances

DMT:
Resin, powder or tarry mass

5-MeO-DMT:
crystalline mixture

Ayahuasca is a shamanic herbal potion made from DMT-containing chacruna leaves (Psychotria viridis) and the harmaline-containing ayahuasca liana Banisteriopsis caapi. Harmaline is an MAO inhibitor. MAO inhibitors are substances and drugs that prevent the enzyme MAO from breaking down both endogenous messengers such as adrenaline, dopamine, serotonin, etc., and foreign alkaloids such as caffeine, cocaine, etc. MAO normally also degrades the active substance DMT even before it can enter the central nervous system via the blood-brain barrier.

Changa is a mixture for smoking of DMT-containing plants (but usually mostly crystalline DMT) and herbs that act as MAO inhibitors.

Risks

The risk associated with the use of DMT and 5MeO-DMT lies primarily in the psychological area and depends on the personality structure of the user. The perceptual changes during a trip can be so intense that inexperienced users in particular feel overwhelmed by the flood of impressions. Perceiving sudden bursts of emotion can also be perceived as rather disturbing and overwhelming. At high doses, especially 5-MeO DMT, such psychological side effects can be felt for days to weeks. If the rules of the set and setting are not followed, there may be false reactions, loss of orientation, panic, paranoia, and horror trips. Physical side effects include nausea, vomiting, increase in heart rate, slightly accelerated breathing, increased blood pressure, pupil dilation, increased salivation, tremors, restlessness, headaches, and movement disorders.

Long-term risks
Permanent disturbances in self- and reality recognition are possible. The worldview may be permanently challenged, which can make it difficult to cope with everyday life. Latent (hidden) psychoses may be triggered.

Safer Use

Take DMT/5-MeO-DMT while sitting or lying down, as physical perception and ability to move are impaired during intoxication.
The consumption of MAO-inhibiting foods such as matured cheese, smoked fish or meat, sauerkraut, tofu, chocolate etc. should be avoided before and after consumption.
People with high blood pressure should not consume DMT/5-MeO-DMT.
Use DMT/5-MeO-DMT only well-prepared in a stress-free environment (no party drugs!), in which you feel comfortable. Preferably with experienced friends you trust (favorable setting).
Take DMT/5-MeO-DMT only when you feel in good mental and physical condition (favorable set).
You should not be afraid, but have enough respect for the effect.
In delicate moments during the trip: let yourself go, try not to fight the effect. A trip sitter can help you.
In case of panic attacks or horror trips: see General Information under Emergency.
Dextrose can help against circulatory problems.
Avoid roads and other "dangerous" places, your orientation may be impaired.
Psychedelic trips should remain exceptional experiences and should definitely not be experienced more than once a month.
After the trip, allow yourself plenty of rest and recovery, at least the day after, to be able to process the experience.
Persons with mental problems or illnesses, persons taking neuroleptics, and persons with circulatory and cardiac problems should refrain from consuming DMT/5-MeO-DMT.

Mixed use

Refrain from mixed consumption! Taking DMT/5-MeO-DMT with alcohol or various medicines (especially MAO inhibitors) can lead to extremely strong and/or unpleasant side effects, for example extremely high blood pressure.
Refrain from mixed use with lithium. There is an increased risk of psychosis and stroke.
Do not consume tramadol if you use psychedelic substances. Tramadol lowers the threshold for strokes, while psychedelic substances can trigger them in susceptible individuals.
Cannabis can have unexpected strong effects in combination with psychedelic substances, leading to anxiety, panic attacks and paranoia. Mixed use is discouraged or recommended, dosing cannabis lower than usual and taking long breaks in between.

Substances

3-CMC (Clophedrone)

3-MMC (3-methylmethcathinone)

4-FA

4-MMC (mephedrone)

6-APB

DOM - DOI - DOB

MDA - MDEA - MBDB

Methylone

Synthetic cannabinoids

Extender

No items found.

LSD analogues

LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.

Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.

In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.

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DMT - Changa - Ayahuasca - 5-MeO-DMT

Effect

Duration

Dosage

Risks

Medicines

Emergency

Things to know

Current warnings

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Effect

Duration

Dosage

Risks

Effect

Dosage

Risks

Safer Use

Mixed use

Substances

Sex

Extender

LSD analogues

Medicines

Synthesis impurities

Emergency

Things to know

Current warnings

Advisory service

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