Quick info

DMT (N,N-dimethyltryptamine) is a naturally occurring psychedelic found in plants, animals and humans, but is usually sold in extracted form as a crystalline powder.
Changa is a mixture of plants containing DMT (usually crystalline DMT) and herbs for smoking
Ayahuasca is a shamanic herbal potion made from DMT-containing chacruna leaves (Psychotria viridis) and the harmaline-containing ayahuasca liana Banisteriopsis caapi.
5-MeO-DMT is structurally related to DMT and is usually present in crystalline form. The effect is comparable to that of DMT, but 5-MeO-DMT is more potent than DMT and is therefore dosed much lower.
With smoked and snorted DMT, the onset of effect is usually perceived as overwhelming in terms of speed and intensity. With all forms of consumption, euphoric feelings can arise as well as an altered, greatly slowed sense of time. Immersion in very bizarre worlds, separation of body and mind, ego dissolution, and a sense of oneness with matter are often experienced. Physical effects include increased blood pressure and pulse, and dilation of the pupils.
Onset of action
DMT
Smoked: after a few seconds
Swallowed: after 30 - 60 minutes
5-MeO-DMT
smoked: after a few seconds
snorted: after a few minutes
Duration of effect
DMT
smoked: 5 - 20 minutes
Ayahuasca:
1 - 6 hours, but can linger for 1 - 8 hours (!). Higher doses of ayahuasca lead to a prolongation of the effect.
5-MeO-DMT
smoked: 5 - 20 minutes
snorted: 30 - 45 minutes The high usually lingers for 1 - 2 hours.
Dosage
DMT
smoked: 15 - 60 mg (only possible in a glass pipe)
snorted: 20 - 50 mg
swallowed: 30 - 150 mg
Changa:
Depending on the actual DMT content.
Ayahuasca:
Dependent on actual DMT content.
5-MeO-DMT
smoked 2 - 15 mg
snorted: 2 - 20 mg
injected 2 - 3 mg
5-MeO-DMT must be dosed very carefully, as even a few milligrams more can cause a very intense and unpleasant effect that can involve psychological and mental problems lasting several weeks.
Appearances
DMT:
Resin, powder or tarry mass
5-MeO-DMT:
crystalline mixture
Ayahuasca is a shamanic herbal potion made from DMT-containing chacruna leaves (Psychotria viridis) and the harmaline-containing ayahuasca liana Banisteriopsis caapi. Harmaline is an MAO inhibitor. MAO inhibitors are substances and drugs that prevent the enzyme MAO from breaking down both endogenous messengers such as adrenaline, dopamine, serotonin, etc., and foreign alkaloids such as caffeine, cocaine, etc. MAO normally also degrades the active substance DMT even before it can enter the central nervous system via the blood-brain barrier.
Changa is a mixture for smoking of DMT-containing plants (but usually mostly crystalline DMT) and herbs that act as MAO inhibitors.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
We are not aware of any extenders for DMT/Changa/Ayahuasca/5-MeO-DMT.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.