Oxycodone

Oxycodone has analgesic, depressant, antianxiety, cough suppressant and psychotropic properties. More intense dreams may also occur. Due to its relaxing and euphoric properties, it is used as a recreational drug, and is said to be more stimulating and mood-lifting than other opioids.

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Onset of effect

Injected: after a few seconds
Snorted: after 2-3 minutes
Swallowed: after 20-40 minutes

Duration of action

approx. 3-6 hours

Appearance

As tablets, capsules, drops and solution for injection/infusion. Sustained-release or non-retarded. Also available as a combination preparation with the opioid antagonist naloxone: this to reduce constipation and to make it unattractive for abuse.

Swallowed

Light: 2.5 - 10 mg
Medium: 10 - 25 mg
Strong: 25 - 40 mg

Snuffed (as a nasal spray)

Light: 2.5 - 7.5 mg
Medium: 7.5 - 15 mg
Strong: 15 - 25 mg

When consuming for the first time, low doses should be used, as the risk of respiratory arrest is increased.

Mixing with other downers (alcohol, benzodiazepines, drugs, GHB/GBL, heroin, opioids) can lead to dangerous interactions and an intensification of the effect and there is a risk of respiratory depression up to respiratory paralysis, a drop in blood pressure, a coma and in the worst case can lead to death!

The combination with methoxetamine (MXE, Metha-Keta) increases the opioid effect.

Mixing opioids with DXM is generally not recommended - there is an increased risk of central nervous system disorders as well as heart and respiratory problems. In addition, DXM lowers the individual opioid tolerance, which is why the risk of overdose increases considerably.

Mixed use of opioids with stimulants (such as cocaine, amphetamine, methamphetamine) puts extreme strain on the body and the cardiovascular system. The effects can mask each other, so that they are subjectively felt to be weaker. If the effect of the stimulants wears off before the opioids, there is a risk of delayed overdose and even respiratory depression.

Opioids are highly effective medications that should only be used for a limited time and, at best, with a doctor's supervision.

Start with a low dose and wait for the effect and tolerance before adding more.

After a period of abstinence, use a much lower dose! The usual dose before the abstinence phase can otherwise quickly have life-threatening consequences.

If you inject opioids, dose even more carefully, as the range between desired effect (rush) and dangerous overdose is even more difficult to assess. Avoid injecting opioids; the risk of overdose is particularly high. Always use new (clean and sterile) injection material! Never exchange syringes, filters, water, disinfection swabs to avoid transmission of hepatitis and HIV.

Do not rely on dosage information from colleagues who regularly use opioids. Due to habituation or dependence, their doses are significantly higher and can be fatal for new users.

Take longer breaks (at least several days) between consumption.

Refrain from citrus fruits (especially grapefruit) before or during consumption. The combination can lead to an increase in the effect of the opioid and/or respiratory depression.