Quick info

Morphine (derived from Morpheus, the Greek god of dreams) is the strongest naturally occurring painkiller from the group of opiates and is extracted from the milky sap of the opium poppy. It serves as a prototype for all opiates, i.e. the potency of other opioid analgesics is given in comparison to morphine.
Due to its strong analgesic, antitussive and psychotropic properties, morphine is used to treat severe pain in emergency and palliative care.
Due to its depressant and sedative effect, the active substance is also misused as a euphoric intoxicant. In the context of opioid agonist therapy, morphine is used as a substitute for opiate/heroin addiction.
Onset of effect
Injected: after seconds
Swallowed: after approx. 20 minutes (for sustained release tablets after 1 - 1.5 hours)
Duration of action
approx. 3 - 6 hours
Swallowed:
Light: 5 - 10 mg
Medium: 15 - 20 mg
Strong: over 25 mg
When consuming for the first time, low doses should be used, as the risk of respiratory arrest is increased.
Risks
Gastrointestinal complaints such as constipation are common side effects after taking opiates. Nausea, vomiting, dry mouth, lack of appetite, abdominal pain, sweating, skin rashes, itching, dizziness, headaches and fatigue are other common complaints. On the psychological level, confusion, nightmares and hallucinations may occur. Rather rarely, there is a drop in blood pressure, breathing difficulties and allergic reactions.
Overdose
Overdoses with morphine are life-threatening, as the substance has a strong respiratory depressant effect (worsening breathing) even in low doses, which can lead to respiratory arrest and coma. Oral consumption of 0.3 - 1.5 g and intravenous consumption of 100 mg can lead to a fatal overdose. In opioid addicts, the lethal dose can be significantly higher. An overdose is treated by taking naloxone, an opioid antagonist.
Long-term risks/consequences
The consumption of morphine can lead to physical and psychological dependence after only a short time. Tolerance builds up quickly, which is why higher and higher doses have to be consumed. Strong withdrawal symptoms such as restlessness, irritability, depression, insomnia, sweating, cold shivers, vomiting, diarrhoea and painful cramps may occur. Like all opiates, morphine can lead to chronic constipation.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.