Benylin® with Codeine N, Codeine Knoll®, Codicalm®, Escotussin, Néo-Codion® N, Paracodin®, Resyl® plus, Gelonida® etc.
Codeine is a substance found in opium and belongs to the group of opiates. In medicine, codeine is used as a painkiller (mostly in combination with paracetamol) and as a cough suppressant.
The effect is individual and dose-dependent. It varies from sedative and analgesic effects, mild sedation to euphoria or excitement. In high doses (100-200 mg) codeine is strongly sedating.
Onset of effect
Varies with the form of application.
Swallowed: 15 - 90 minutes
Snorted and rectally (suppositories): after approx. 10 minutes
Injected: after a few seconds
Duration of action
Swallowed: 4 - 12 hours
Snorted 3 - 6 hours
light: 20 - 100 mg
medium: 100 - 150 mg
strong: 150 - max. 200 mg/day
The effect occurs more quickly when codeine is mixed with carbonic acid and sugar. From 100 mg, a strong sedative and depressant effect can already occur. Higher doses mainly increase the risk of side effects. An increase in effect at high doses is rarely seen, as the body can only absorb limited amounts of codeine.
Appearances
Mono- and combination preparations in the form of tablets, capsules, pastilles, drops or syrup, rarely in suppositories.
A mixture of codeine, crushed candy in sweet drinks (often lemonade) is called Lean, Texas Tea, Purple Drank, or Sizzurp.
Risks
Nausea, vomiting, dizziness, itching, sweating, constipation, feeling cold, dry mouth, headache, loss of appetite, abdominal cramps, slowed pulse, sleep disturbances.
At higher doses (overdose or in combination with other downers), other severe side effects may also occur: Numbing sensation, slowing and attenuation of breathing to respiratory arrest, severe drowsiness to unconsciousness, life-threatening shock, visual disturbances.
Long-term risks/consequences
Tolerance development is the habituation to an opiate, whereby its effects diminish through repeated or chronic use over a period of time.
Dependence is accompanied by physical and psychological symptoms and can develop with regular use. Withdrawal symptoms in case of addiction could be: compulsive craving for opioids, anxiety or agitation, nausea, vomiting, diarrhea, sleep disturbance, runny nose, sneezing.
After opiate withdrawal, tolerance to opioids is lost, meaning that one becomes as sensitive to opioids as before dependence. The risk of intoxication is particularly high if the dose consumed again is not drastically reduced compared to the doses before withdrawal.
The simultaneous consumption of depressant substances such as alcohol, ketamine, GHB/GBL, nitrous oxide, benzodiazepines and/or other opioids/opiates is dangerous, as there is an increased risk of vomiting and unconsciousness. The risk of suffocation is high!
The combination with methoxetamine (MXE, Metha-Keta) increases the opioid effect.
Mixed use of opioids with DXM is generally not recommended - there is an increased risk of central nervous system disorders as well as cardiac and respiratory problems. In addition, DXM lowers the individual opioid tolerance, which is why the risk of overdose increases considerably.
Mixed use of opiates with stimulants (such as cocaine, amphetamine, methamphetamine) puts extreme strain on the body and cardiovascular system. The effects can mask each other, so that they are subjectively felt to be weaker. If the effect of the stimulants wears off before the opioids, there is a risk of delayed overdose and even respiratory depression.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.