Methylphenidate (Ritalin®)

Taking methylphenidate increases the concentration of the nerve messengers dopamine, noradrenaline and serotonin in the brain. When prescribed for ADHD, the drug is supposed to act as a filter for incoming stimuli and alleviate symptoms such as distractibility, attention deficit disorder, disorganisation and impulsivity.

However, due to its stimulating, energising and drive-enhancing properties, methylphenidate is also used as a party drug or to increase performance. Due to the increased release of dopamine, similar effects occur as with the use of cocaine.

Onset of effect

after approx. 30 minutes (after up to 2 hours in the retarded form).

Duration of action

approx. 4 - 8 hours (in the case of sustained-release tablets, the active substance is released with a delay over a longer period).

Light: 20 - 40 mg
Medium: 40 - 60 mg
Strong: 60 - 80 mg

Ritalin is swallowed, snorted, rarely smoked or injected.

• Alcohol can increase the (undesirable) effects of methylphenidate.
• The mixed use of methylphenidate with other serotonergic substances (such as MDMA, amphetamine, methamphetamine) increases the risk of serotonin syndrome.
• Methylphenidate should not be combined with MAO inhibitors (such as certain antidepressants or neuroleptics). Complications may still occur up to 2 weeks after discontinuation of an MAO inhibitor.
• Take care when mixing with psychedelic substances (such as LSD, DMT, mescaline, etc.). The combination with methylphenidate can increase feelings of anxiety and circling thoughts.
• Mixed use of methylphenidate and tramadol should be avoided, as both substances increase the risk of stroke.

• Do not consume methylphenidate intravenously. Due to the tablet substances it contains, embolism (blockage of pulmonary or cerebral vessels) may occur.
• If you consume methylphenidate nasally, observe the safer-sniffing messages

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