Quick info
Tramal®, Tramundin®, Tradonal®, Travex®, Ecodolor®, Adamon®, Amadol®, etc.
Tramadol is an analgesic agent for the treatment of moderate to severe pain and belongs to the group of opioid analgesics. Tramadol is generally considered to be very well tolerated by the human body and has therefore been available on the market in Switzerland since 1977 as a prescription painkiller under the name Tramal®.
Analgesic, anxiety-relieving, euphoric, mood-lifting, causes a general feeling of contentment.
The human body has its own pain-relieving system. The endogenous substance endorphin ensures that pain messages are sent to the human brain in a reduced form by docking to certain receptors in the human body. The active ingredient tramadol has a similar mode of action in that the active ingredient attaches to neurotransmitter docking sites (opioid receptors) and transmits a signal to the brain, which subsequently triggers pain relief. In addition, tramadol inhibits the reuptake of certain nerve messengers (noradrenaline and serotonin), which in turn increases the amount of free messengers in the tissue and supports the analgesic effect.
Duration of action
Swallowed: approx. 4 - 7 hours. After-effects may last up to 12 hours.
Onset of effect
Swallowed: after approx. 60 minutes
Tramadol is mainly taken orally in tablet form or as drops. However, it could theoretically also be snorted and injected. Injections are usually only administered in hospital.
Swallowed:
Mild: 50 - 100 mg
Moderate/Strong: 100 - 250 mg
Above 250 mg, there is a risk of respiratory arrest.
When consuming for the first time, low doses should be used, as the risk of respiratory arrest is increased.
When consuming tramadol, mixed consumption should be avoided if possible!
Mixing with other downers (alcohol, benzodiazepines, drugs, GHB/GBL, heroin, opioids) can lead to dangerous interactions and an intensification of the effect and there is a risk of respiratory depression up to respiratory paralysis, a drop in blood pressure, a coma and in the worst case can lead to death!
Mixed consumption with various antidepressants (e.g. amitriptyline, fluoxetine, citalopram, venlafaxine, etc.) should be particularly emphasized. There is a risk of serotonin syndrome with these combinations. This also applies to mixed use with uppers such as cocaine, MDMA, 4-MMC or amphetamine. This can lead to a high level of stress for the body (circulatory collapse, etc.).
Opioids are highly effective medications that should only be used for a limited time and, at best, with a doctor's supervision.
Start with a low dose and wait for the effect and tolerance before adding more.
After a period of abstinence, use a much lower dose! The usual dose before the abstinence phase can otherwise quickly have life-threatening consequences.
If you inject opioids, dose even more carefully, as the range between desired effect (rush) and dangerous overdose is even more difficult to assess. Avoid injecting opioids; the risk of overdose is particularly high. Always use new (clean and sterile) injection material! Never exchange syringes, filters, water, disinfection swabs to avoid transmission of hepatitis and HIV.
Do not rely on dosage information from colleagues who regularly use opioids. Due to habituation or dependence, their doses are significantly higher and can be fatal for new users.
Take longer breaks (at least several days) between consumption.
Refrain from citrus fruits (especially grapefruit) before or during consumption. The combination can lead to an increase in the effect of the opioid and/or respiratory depression
When consuming tramadol, mixed consumption should be avoided if possible!
Mixing with other downers (alcohol, benzodiazepines, drugs, GHB/GBL, heroin, opioids) can lead to dangerous interactions and an intensification of the effect and there is a risk of respiratory depression up to respiratory paralysis, a drop in blood pressure, a coma and in the worst case can lead to death!
Mixed consumption with various antidepressants (e.g. amitriptyline, fluoxetine, citalopram, venlafaxine, etc.) should be particularly emphasized. There is a risk of serotonin syndrome with these combinations. This also applies to mixed use with uppers such as cocaine, MDMA, 4-MMC or amphetamine. This can lead to a high level of stress for the body (circulatory collapse, etc.).
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Lower risk
Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.
Risk
This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.
