Winstrol®, Deca-Durabolin®, Dianabol®, Oxandrin®, Anavar® etc.
Anabolic androgenic steroids (AAS) are synthetically produced active ingredients with anabolic (building) and androgenic (masculinizing) properties. They increase skeletal muscle development, promote physical performance, and reduce body fat. AAS include pharmaceutical drugs that have been developed for use in humans or are still in the clinical testing phase, as well as products from veterinary medicine and synthetic designer substances that have not yet been tested in humans.
Medically, testosterone and other AAS are taken as drugs for hypogonadism. This is an underfunction of the gonads and testicles of the male, which leads to a restriction of testosterone production and the development into a male body (feminization process). Other possible medical applications are anorexia (against loss of appetite), cachexia (against weight loss), osteoporosis (against bone loss) or muscular dystrophies (against muscle atrophy).
In (amateur) sports, AAS are used to enhance performance and as an illegal doping agent. In professional sports, the intake and dosage of AAS are controlled to reduce the risk of a positive doping test.
The substances promote the regenerative capacity of the human body, i.e. it can be trained in shorter intervals. Another possible reason for taking them is to increase physical attractiveness and sexual performance.
In muscle training, a distinction is made between two phases: muscle building (bulking) and muscle definition (cutting). For both phases, there are different AAS that are used specifically. However, there are also so-called "allrounder" AAS, which are used for both phases. In addition, dehydrating and fat-burning drugs are used. These are taken as "additives" in the build-up and definition phase. These substances cause the muscles to become particularly prominent and visible due to the loss of body water. These additives are diuretics (synthetic dehydrating substances) and sympathomimetics or thyroid hormones (fat-burning substances).
Human growth hormones such as insulin-like growth factor-1 (IGF-1), insulin, sympathomimetics (mainly clenbuterol), and newly selective androgen receptor modulators are also frequently used. AAS only work in the body as long as they are taken. As soon as AAS are discontinued, a large part of the muscle mass disappears.
AAS drugs have performance-enhancing, growth-promoting, euphoric, sexually stimulating, fat-burning and appetite-enhancing effects.
Ampoules (liquid), tablets, capsules, patches, chewing gum, plasters and gels
AAS are mainly administered orally in tablet form or by injection into the muscle. Other forms of administration are via the oral mucosa (buccal, e.g. with chewing gums containing active ingredients) or via the skin (transdermal, with patches or gels containing active ingredients).
A major difference in the use of these substances compared to psychoactive substances is that the hoped-for reward effect occurs with a delay. The desired effect on body image usually occurs with a delay of weeks or months, although the positive effects on libido and psychological well-being begin earlier.
During the intake phase, users of AAS combine different AAS and other different substances over a period of several weeks (stacking). In this context, the users speak of a "cycle" or a "cure". In most cases, the dose of medication is increased toward the middle of the intake period and decreased again toward the end (pyramiding). The goal of these strategies is to take advantage of synergistic anabolic effects, reduce side effects, and accelerate physical and mental recovery after overuse of these substances.
Duration of action
The effect depends strongly on the substance taken, the dosage and the frequency of use. The dosage in popular sports is often many times higher than the usual medical dosage, which is associated with corresponding risks.
Taking AAS as part of a cycle of AAS lasts an average of 12 weeks.
Varies greatly depending on the active ingredient and individual metabolism. Take only on medical prescription!
The various side effects that occur during or after consumption can be very severe and depend, among other things, on the dosage and the particular drug.
Side effects of AAS may present as follows:
Acne and other skin irritations, hair loss, body weight gain, irritability, aggressiveness, sexual dysfunction, increased water retention in the body, mood swings, nausea, emotional swings, sleep disturbances, increased sweating. Damage to the cardiovascular system, changes in the heart muscle (during sports activities, the heart muscle may be undersupplied with oxygen), increased blood pressure (hypertension), cognitive impairment such as decrease in the ability to concentrate and memory. After a single intake, the blood count may already change.
In addition, it can take weeks to months after a cycle to restore normal natural testosterone levels. This depends on the dosage and amount of substances used in the cycle. However, it may happen that the production of testosterone remains limited.
Due to the frequent occurrence of false declarations and substances of inferior quality, additional unknown risks and side effects are to be expected.
In women, AAS can cause a change in the menstrual cycle, enlargement of the clitoris, a change in body hair (e.g., beard growth), and a deepening of the voice.
In case of improper injection, there is a risk of bacterial or viral infections (e.g. HIV), abscesses or tissue necrosis.
Regular and long-term use can lead to psychological and physical dependence (including craving symptoms, development of tolerance), depression (even after discontinuation of the substance), liver damage, kidney damage, personality changes, gynecomastia (breast enlargement in males), testicular atrophy (shrinkage of the testicles), virilization (masculinization), growth disturbance in adolescents, respiratory diseases, voice disorders, cardiovascular diseases, and increased risk of cancer.
- If AAS are obtained on the black market or on the Internet and not from a pharmacy/medical facility, the content is unclear. Many drugs are misdeclared or the content is of inferior quality.
- Eat a healthy diet and make sure that you consume plenty of vitamin-, protein- and carbohydrate-rich drinks and meals. It also makes sense to eat several small meals throughout the day, as the body needs a lot of energy due to the large muscle mass and the intense training.
- The intake of AAS or the "cure" should always be accompanied by a medical professional and regular blood value and organ examinations should be performed.
- Immediate discontinuation of anabolic steroids may result in withdrawal symptoms with prominent discontinuation phenomena. Discontinuation should be medically supervised.
- Use of AAS can lead to severe mood swings, including aggressiveness, agitation, restlessness, impulsivity, depression, and even mania.
- Do not overload your body during training! Avoid mixed use with painkillers and stimulants (amphetamine, cocaine, etc.). This can be very stressful for the body (cardiovascular system, organs, etc.) and cause harmful short- and long-term effects.
- Caution - Safer Sex: Taking AAS may cause a change in sexual behavior through increased libido and sexual performance. This disinhibition may lead to engaging in high-risk sexual practices that increase the risk of injury.
- Attention - Safer Injection: Pay attention to clean injection techniques. Always use new (clean and sterile) injection material! Never exchange syringes, filters, water, disinfection swabs to avoid transmission of hepatitis and HIV.
When consuming AAS, mixed consumption should be avoided!
Especially the mixed use with uppers (cocaine, amphetamine, etc.) can lead to a high load for the body. The cardiovascular system is very heavily loaded by this combination. Special care should be taken during activities with high physical stress (e.g. activity in a fitness center). There is an increased risk of cardiac arrest.
There is also a risk of sexual disinhibition and mood swings when mixed with psychoactive substances.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.