Mephedrone, also known as 4-MMC, is a synthetically produced cathinone derivative, a subgroup of amphetamines. It belongs to the group of stimulants.
Mephedrone is closely related to methcathinone and differs from it only by a methly group at the para position. After the almost worldwide ban of mephedrone, other cathinones (e.g. 3-MMC) with similar effects came onto the market.
The effect is similar to that of methcathinone, cocaine and MDMA. Mephedrone causes euphoria and stimulation, increased urge to talk, increased performance and altered sensory perceptions. In addition, libido is stimulated. The need for food and sleep is suppressed.
Onset of action:
Snorted and swallowed: after 15-30 minutes.
Duration of action:
Snorted 3-6 hours, swallowed 4-8 hours.
Light: 15-45 mg
Medium: 45-80 mg
Strong: 80-125 mg
Light: 50-100 mg
Medium: 100-200 mg
Strong: 200-300 mg
Little is known about intravenous, rectal, and inhalation use. These forms of consumption should be avoided; if they are, dose as low as possible.
Various adverse effects may occur when consuming mephedrone: Dry mouth, mydriasis (dilated pupils), jaw grinding, increased heartbeat, increase in body temperature, anxiety or paranoia. There is a risk of dehydration due to decreased thirst and lack of fluid intake. High doses of mephedrone lead to psychotic reactions and can increase schizophrenia. There is a risk of dependence with symptoms such as restlessness, tremors, insomnia and hyperactivity.
Mephedrone is a new psychoactive substance. To date, nothing is known about the exact mechanisms of action, toxicity and possible long-term effects. The current state of knowledge is based almost exclusively on reports from users. Due to the strong craving (irresistible and uncontrollable desire to consume), especially when snorting or smoking the substance, there is a risk that it will be taken too quickly and the side effects will predominate.
There is little knowledge about new psychoactive substances. When you use them, you are exposing yourself to unknown risks. Have the substance analyzed in a drug checking. If this is not possible and you still want to use, then feel your way to the desired dose with small amounts.
If you decide to use, be as informed as possible about the specific substance and the appropriate dosage - Also, with NPS, consider your basic mood and the environment in which you use (set and setting).
Do not buy a product with a fancy name without a declaration of the ingredient. Legal does not mean harmless.
During consumption, inform your friends about what and how much you have consumed.
Drink enough non-alcoholic beverages and get some fresh air in between.
Accept it when the effect runs out, don't add to it right away.
Refrain from mixed consumption, as interactions are dangerous and unexplored.
Take regular breaks from consumption.
People with high blood pressure, heart problems, hyperthyroidism, liver and kidney disease, or circulatory problems should not take New Psychoactive Substances.
Refrain from using mephedrone and other serotonin releasing substances such as MAOIs, MDMA, 4-FA, methamphetamine, methylone, 5-HTP and SSRIs/SNRIs. A life-threatening serotonin syndrome can occur!
Mixed use with 25x-NBOMe and 25x-NBOH can lead to excessive stimulation with panic attacks, seizures, mind spinning, increased blood pressure, vasoconstriction, and in severe cases can lead to heart failure.
Do not take tramadol if you use stimulants. Tramadol and stimulants can both cause strokes, which cumulates the risk.
Other potentially harmful combinations cannot be ruled out, as there is no scientifically sound information on interactions with cathinones.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.