Substances / GHB - GBL

GBL (gamma-butyrolactone) and BDO (1,4-butanediol) are GHB precursors, i.e. they are converted by the body into GHB. GHB is closely related to endogenous gamma-aminobutyric acid (GABA) and activates certain GABA receptors. GABA is the most important inhibitory neurotransmitter in the brain and regulates sleep-wake cycles, memory functions and growth hormones, among other things. GHB/GBL/BDO can have stimulating as well as relaxing and calming effects, depending on the phase of action, dosage and individual metabolism. In medicine, GHB is used in the treatment of narcolepsy and I some countries also against the withdrawal syndrome in alcohol dependence.

Effect

Extremely dose-dependent and individually very different. The spectrum of effects ranges from euphoria, relaxation, disinhibition, increase in sexual desire, intensification of perception, urge to talk (babble flash), slight dizziness, nausea, drowsiness to deep sleep with unconsciousness (film tear).

GHB/GBL/BDO have a sexually stimulating effect and change consciousness at the same time. Under the influence you will assess situations differently. If you use GHB/GBL/BDO during sex, clarify limits, practices and protection with your sexual partners before use.

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Duration

Onset of effect

10-20 min. after ingestion

‍Effective duration

1-3 hrs.‍

Aftereffects

2 to 4 hrs.

Dosage

Swallowed:

Low dose

GHB: 7-13 mg/kg body weight; 1-2ml

GBL: 0.5 to 0.9 ml

Average dose

GHB: 14-20 mg/kg body weight; 2-3 ml

GBL: 1.0 to 1.4 ml

High dose

GHB: 21-28 mg/kg body weight; 3-4 ml

GBL: 1.5-2.0 ml

Narcotic dose

GHB: > 28 mg/kg body weight; > 4ml

GBL: > 2.0 ml

The dosage depends on the degree of dilution and is even more delicate with GBL than with GHB, as not every body converts GBL into GHB at the same rate and in the same amount. GBL is a strong acid that can corrode the mucous membranes and must be heavily diluted with a non-alcoholic drink before drinking! In case of doubt: less is more!

Risks

The higher the dose, the more likely headache, nausea, confusion, dizziness, uncontrollable muscle twitching, or unconsciousness will occur.

Already a deviation of one milliliter or the mixture with alcohol, sedatives or opiates can lead to overdose and life-threatening consequences up to death (respiratory depression!). Signs of an overdose are undisturbed or hardly disturbed sleep, unconsciousness, disappearance of reflexes and breathing difficulties. It is difficult to assess whether someone is only in deep sleep or is already in a life-threatening coma - if in doubt, always seek medical help.

Long-term risks:
Regular use can lead to sleep disturbances, anxiety and tremors; there is a risk of dependence with psychological and physical symptoms. Chronic high-dose use (multiple doses daily) results in severe physical withdrawal symptoms such as epileptic seizures upon discontinuation, which can be life-threatening. Regular use of high doses of GHB and especially repeated unconsciousness resulting from GHB ingestion (or mixed use with GHB) have a high risk of developing persistent disturbances in thinking and intellectual performance.

Safer Use

The substances are odorless. GHB tastes salty, GBL/BDO soapy. GBL has a strong corrosive effect, irritates the mucous membranes and stresses the liver.
Dilute GHB/GBL/BDO before taking it with a non-alcoholic beverage.
Refrain from mixed consumption of any kind. Mixed use with alcohol, benzodiazepines and other tranquilizers as well as opiates (including codeine) can lead to life-threatening respiratory paralysis even in small amounts.
Even if GHB/GBL/BDO does not work (yet), do not add more right away. Often, adding more leads to an unintentional overdose.
Refrain from consuming GHB/GBL/BDO when you are alone.
People with epilepsy, heart, liver, or kidney dysfunction take life-threatening risks when they consume it.
After regular use (daily), perform withdrawal only under medical supervision, as it can be life-threatening.

Mixed use

Consumption of alcohol before, during or after GHB/GBL use can lead to collapse even with small amounts of alcohol (risk of respiratory paralysis!). Mixed consumption with antiretroviral drugs (protease inhibitors, e.g. Kaletra, Reyataz, Crixivan, Norvir, Invirase) can intensify the effect of GHB/GBL in a life-threatening way even at low doses (risk of respiratory depression, coma, epileptic seizures!).

Substances

3-CMC (Clophedrone)

3-MMC (3-methylmethcathinone)

4-FA

4-MMC (mephedrone)

6-APB

DOM - DOI - DOB

MDA - MDEA - MBDB

Methylone

Synthetic cannabinoids

Sex

Increased risk behaviour due to disinhibiting effect and increased sexual desire. Also abused to make others sexually compliant ("knockout drops").

Extender

No items found.

LSD analogues

LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.

Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.

In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.

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GHB - GBL - BDO

Effect

Duration

Dosage

Risks

Medicines

Emergency

Things to know

Current warnings

Advisory service

Downloads

Effect

Duration

Dosage

Risks

Effect

Dosage

Risks

Safer Use

Mixed use

Substances

Sex

Extender

LSD analogues

Medicines

Synthesis impurities

Emergency

Things to know

Current warnings

Advisory service

Downloads