Quick info
GHB and GBL are synthetically produced and used in pharmacology and industry respectively. They belong to the group of depressants.
The effect is extremely dose-dependent and varies greatly from individual to individual. It also depends on the purity of the substance. The spectrum of effects ranges from euphoria, relaxation, disinhibition, intensification of perception, urge to talk (babble flash), slight dizziness and drowsiness to deep (coma-like) sleep or unconsciousness.
Swallowed:
GHB: 7 - 30 mg/kg body weight, or 1 - 5 ml, depending on the person's habituation and body weight.
GBL: 0.6 - 2 ml, depending on the degree of dilution.
The dosage depends on the degree of dilution and is even more delicate with GBL than with GHB, as not every body converts GBL into GHB at the same rate and in the same amount. GBL is a strong acid that can corrode the mucous membranes and must be heavily diluted with a non-alcoholic drink before drinking! In case of doubt: less is more!
Onset of action
GHB swallowed: after 10 - 20 minutes
GBL swallowed: after approx. 5 minutes
Duration of action
1.5 - 4 hours. In rare cases, the effect can last up to one day. Since GBL has a higher bioavailability than GHB (i.e. a greater proportion of the active ingredient reaches the brain more quickly), it has a faster and stronger effect than GHB, even if it is first converted to GHB in the body.
The higher the dose, the more likely nausea, vomiting and dizziness will occur. Headaches, confusion, breathing difficulties, cardiac arrhythmias, impaired balance and memory can occur at very high doses, as can uncontrollable muscle twitching, which is easily mistaken for epilepsy but can also progress into epilepsy.
The danger of an unintentional overdose is very high with GHB/GBL - even if it is not mixed! Signs of a GHB/GBL overdose are severe drowsiness followed by several hours of deep sleep that cannot be disturbed or can only be disturbed with difficulty (sometimes interrupted by short periods of wakefulness = standing man symptom), mild to very severe nausea, nausea, dizziness, headache, muscle atrophy (barely able to stay on one's feet) up to complete immobility, unconsciousness, disappearance of reflexes and breathing difficulties. It is difficult to assess whether users are only in a deep sleep or already in a coma after GHB/GBL use - if in doubt, always seek medical help!
Long-term risks:
Regular use of GHB/GBL can lead to sleep disorders, anxiety and tremors; there is a risk of dependence with psychological and physical symptoms. In the case of chronic high-dose consumption (several doses daily), severe physical withdrawal symptoms such as sweating, muscle cramps or epileptic seizures occur upon discontinuation.
If you are offered GHB/GBL, ask about the origin of the substance and the dosage.
GBL should be dosed lower than GHB! To produce the same effect, you need about half as much GBL as GHB.
Dose carefully! If GHB/GBL does not (yet) work, it is best to wait 2 hours and not add more right away. Often, overdosing is caused by adding more. Use an insulin syringe or graduated pipettes so that you can measure your unit of consumption accurately. Make a note of when you took your last dose.
Refrain from using GHB/GBL when you are alone.
With GHB/GBL, refrain from mixed consumption of any kind, especially with alcohol! Dilute the liquid before consumption, e.g. with tea.
If you have sex on GHB/GBL, follow the safe sex rules. Have condoms etc. ready before consumption.
People with epilepsy, heart or kidney dysfunction should not consume GHB/GBL under any circumstances!
GHB/GBL withdrawal should only be carried out under medical supervision.
Never leave your drink unattended to avoid someone mixing GHB/GBL into your drink. If your drink tastes strange, pour it out for your own safety.
Consumption of alcohol before, during or after GHB/GBL use can lead to collapse even with small amounts of alcohol (risk of respiratory paralysis!). Mixed consumption with antiretroviral drugs (protease inhibitors, e.g. Kaletra, Reyataz, Crixivan, Norvir, Invirase) can intensify the effect of GHB/GBL in a life-threatening way even at low doses (risk of respiratory depression, coma, epileptic seizures!).
Increased risk behaviour due to disinhibiting effect and increased sexual desire. Also abused to make others sexually compliant ("knockout drops").
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.