Laughing gas (N2O, nitrous oxide) is produced synthetically and used in medicine as a narcotic. Laughing gas belongs to the group of dissociatives.
Relaxation, euphoria, optical and acoustic changes in perception, loss of the sense of time.
Onset of action:
a fewseconds after ingestion.
Duration of effect:
approx. 30 seconds to 5 minutes
Nitrous oxide is usually inhaled from balloons or gas cartridges (cream blowers).
Inhaled
light: 4-8 g (½ to whole capsule)
medium: 8 - 16 g (1-2 capsules)
strong: 16 - 40 g (2-5 capsules)
The "body high" begins a few seconds after ingestion with the sensation of a mixture of cold, warm, sharp, and soft tingling that begins in the head and face at lower dosages but spreads to the entire body at higher dosages.
Appearance
Colorless gas
Mild nausea, headache, flatulence, peripheral neuropathy (burning, tingling (in extremities), numbness, muscle cramps, twitching, etc.); in case of excessive consumption, unconsciousness, hallucinations (in very high doses), drop in blood pressure, cardiac arrhythmia, in the worst case death by respiratory paralysis. Risk of asphyxiation in case of insufficient oxygen supply, increased risk of injury due to falls when "stepping away", brain and organ damage (if N2O in the breath exceeds 90%), strong craving.
Long-term risks
Continuous use of nitrous oxide stresses the nervous system and leads to a deficiency of vitamin B12 (risk of disturbed cell function and temporary infertility). Dependence with psychological symptoms is possible, liver and kidney damage, feelings of exhaustion (asthenia), musculoskeletal disorders and numbness in extremities (paresthesia): Laughing gas interferes with the mechanism of action of vitamin B12, which is involved in the normal functioning of the nervous system, concentration or memory difficulties.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.