"New Psychoactive Substances" (NPS) is a collective term for largely unexplored synthetic substances with psychoactive effects. Alternatively, these substances are also called research chemicals (RC's).
NPS are largely unexplored synthetic substances with psychoactive effects. NPS exist in different substance groups: typical are cathinones, tryptamines, phenylethylamines, piperazines, benzodiazepines. Examples are: Mephedrone, Methylone, 3-MMC, 1cP-LSD, Flualprazolam etc. By changing the chemical structure of existing, mostly illegal substances, new substances are "designed" that do not fall under the narcotics law. Often New Psychoactive Substances are marketed on the Internet. On the black market, NPS are sometimes also sold as ecstasy, amphetamine or LSD.
Attention. Even if NPS are sold legally, they are not less dangerous than illegal substances! There are known cases of false declaration (product contains other substance than stated). If possible, have all substances analyzed in a drug checking before consumption.
Before experimenting, learn as much as you can about the specific substance and the appropriate dosage. Also with NPS, pay attention to your mood and the environment in which you use (set and setting).
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.