Quick info

Mescaline is a naturally occurring hallucinogenic substance from the phenethylamine class of substances. Cacti containing mescaline have been used for ritual purposes in Latin America for thousands of years. Mescaline is traditionally used in Latin America by indigenous shamans in rituals.

Mescaline is found in the Central American peyote cactus (Lophophora Williamsii) or the South American cactus genus Trichocereus (T. pachanoi, T. bridgesii, T. peruvianus). Other cactus species, such as the San Pedro cactus native to the Andes region, also contain mescaline.

Effect

Dosage

Risks

Safer Use

Mixed use

Sex

Extender

LSD analogues

Synthesis impurities

Contents

Effect

Mescaline intoxication is described as a psychedelic-visionary, ecstatic state accompanied by feelings of happiness, of great clarity but without the metallic sharpness of LSD.

Nausea and vomiting may often occur before the onset of action.

The trip begins with hyperactivity and inner restlessness, then an altered, sharpened perception and an intense visual effect set in.

In the further course it comes to a gentle drifting experience. Visions and a euphoria of religious depth are reported, the connection with something ancient, the feeling of a visionary experience and the change of ego sensation as well as feelings of ego dissolution.

The coming down phase is softer than with other psychedelics.

Duration

Onset of action
After 45 minutes to 1.5 hours

Duration of action
8 - 14 hours

After-effects
6 - 36 hours

Dosage

Swallowed
light: 50 - 200 mg
medium: 200 - 400 mg
strong: 400 - 800 mg

The mescaline content can vary greatly from plant to plant.

Forms of release
Dried, crushed plant material, filled into capsules or processed directly into a decoction. Mescaline is also available as an extract and in synthetic, crystalline form

Risks

  • Do not consume tramadol if you consume psychedelics. Tramadol lowers the threshold for strokes, while psychedelic substances can trigger them in people who are susceptible to them.
  • Cannabis can have unexpectedly strong effects in combination with psychedelic substances and can lead to anxiety, panic attacks and paranoia. Mixed use is discouraged or it is recommended to use lower doses of cannabis than usual and to take long breaks in between.
  • Mixed use with stimulants (e.g. amphetamine, cocaine , etc.) can increase the euphoric effect of psychedelics, but also increases the risk of psychotic phases, paranoia and thought loops

Safer Use

  • Mescaline is not suitable as a party drug and should only be used by experienced users.
  • Use mescaline only in a well-prepared environment where you feel comfortable and only with experienced friends (good setting) and/or a trip sitter (sober person).
  • Use mescaline only when you feel good mentally and physically (good set).
  • You should not be afraid, but have enough respect for the mescaline effects.
  • Mescaline should be taken on an empty stomach. Fasting before the trip may help to reduce the likelihood of nausea and vomiting.
  • For nausea, it helps if you take mescaline in small doses at a time.
  • Don't throw it right away if it doesn't work right away.
  • Let yourself go during the trip and try not to fight the mescaline effects. A trip sitter can help you with this.
  • Dextrose can help against circulatory problems.
  • Avoid roads and other "dangerous" places, your orientation may be disturbed.
  • Drink enough water during the trip.
  • Avoid mixed consumption at all costs, otherwise the effect can no longer be assessed.
  • Plan enough time for recovery after the trip (at least 1 day).
  • Mescaline trips should remain exceptional experiences.
  • In case of panic attacks or horror trips: stimulus shielding, keeping calm, "talk down/through".
  • People with mental problems or illnesses, people who need to take neuroleptics, and people, with heart problems should refrain from using mescaline.

Mixed use

  • Do not consume tramadol if you consume psychedelics. Tramadol lowers the threshold for strokes, while psychedelic substances can trigger them in people who are susceptible to them.
  • Cannabis can have unexpectedly strong effects in combination with psychedelic substances and can lead to anxiety, panic attacks and paranoia. Mixed use is discouraged or it is recommended to use lower doses of cannabis than usual and to take long breaks in between.
  • Mixed use with stimulants (e.g. amphetamine, cocaine , etc.) can increase the euphoric effect of psychedelics, but also increases the risk of psychotic phases, paranoia and thought loops
Cocaine
No items found.
No items found.
No items found.
No items found.
No items found.

Emergency

If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.

Things to know

Current warnings

Advisory service