Quick info
Ibogaine is an indole alkaloid found in the root of West African plants (e.g., Tabernanthe iboga or Voacanga africana). In low doses, it has a stimulant effect and is used by indigenous people against fatigue, hunger and thirst. Higher doses of ibogaine (from 5-10 mg/kg body weight) have a hallucinogenic effect and are used for ritual ceremonies.
The active ingredient is also known to be an effective agent in the withdrawal of substance dependencies. However, due to various side effects and toxicological findings, ibogaine has only limited approval as a drug.
In low doses, ibogaine has a stimulating effect and suppresses the feeling of hunger and thirst. In higher doses, it evokes intense psychedelic experiences, which, according to testimonials, include insights regarding the meaning of life, the evolution of the universe, or life after death, and can relieve feelings of guilt.
The effect can be roughly divided into three phases: The first 4-8 hours are often described as a dream state in which the individual's experience of visual and other sensory perceptions changes and one remembers earlier life events. The second phase (8-20 hours) is described as evaluative, emotionally neutral, and reflective. This is followed by a phase (up to 72 hours after ingestion) characterized by heightened awareness, mild stimulation, and disturbed sleep patterns. Consumption is accompanied by possible balance disturbances and sleep disturbances.
Ibogaine detox programs are offered in private addiction clinics around the world. One dose is usually sufficient to overcome the addiction. Exactly which active ingredients are responsible for this effect has not yet been fully researched. Certain findings suggest that ibogaine, which is converted to noribogaine in the liver, is stored as a depot in the body and blocks the receptors in the brain that are responsible for the craving for a high. Withdrawal symptoms and the desire to consume (craving) are thereby alleviated. On the psychological level, visions are said to lead directly to the addiction-inducing moment in life. According to reports, those affected are thus able to recognize the cause of the addiction and eliminate addiction-triggering factors. However, the use of ibogaine as a withdrawal aid is controversial.
Swallowed: 5 to max. 22mg per kg body weight.
There is evidence in the literature that, based on limited data from animal studies and applying appropriate safety factors, a maximum initial oral dose of less than 1 mg/kg body weight should be followed for the treatment of addiction. It is advisable to take ibogaine only under the supervision of healthcare professionals, as overdoses can be fatal. There are also individuals who are allergic to ibogaine, so a low dose should be tested.
Appearances
Brownish powder, also in capsule form.
Onset of effect
After 30-180 minutes.
Duration of action
18-36 hours, after-effects are possible up to 72 hours after ingestion.
Side effects may include nausea, vomiting, tremors, dizziness, increased sensitivity to light, low blood pressure, and loss of motor control. Appetite and digestive activity may be impaired. In moderate to high doses, ibogaine has a hallucinogenic effect and a strong perceptual altering effect, which can lead to overstimulation and a "bad trip."
Overdose
High doses can cause convulsions, paralysis, life-threatening cardiac arrhythmias, and death from respiratory failure. It is strongly advised to use ibogaine only in a controlled setting.
Ibogaine is not a party substance. Make sure that the set and setting are suitable - do not use alone and make sure that the environment is as familiar and pleasant as possible. Plan enough time to be able to process the intoxication in peace afterwards.
Only consume when you feel good. If you are afraid of the strong effects, do not use. Do not use if you are afraid of the substance.
Feel your way up to the dose - deaths related to ibogaine overdoses have been reported.
Do not take ibogaine if you have an existing heart condition, as the substance affects your cardiovascular system. Mixing certain medications with ibogaine can also be hazardous to your health.
The effect of iboga occurs only after 1-3 hours. Determine your dose in advance and do not increase it just because you do not feel any effect yet.
Mixing ibogaine with stimulant substances such as cocaine, amphetamines, or even caffeine can lead to cardiovascular problems because ibogaine acts on and blocks the same receptors.
The conversion to noribogaine results in a depot effect, which means that the active substance is still active in the body for 2-4 weeks. While this effect is on the one hand beneficial for the treatment of addiction, it also harbors the risk of possible interactions when consuming substances weeks later.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.