Tremors, restlessness, nausea, palpitations and cardiac arrhythmias, sleep disturbances, headaches, nervousness, irritability and loss of appetite and aggressive behavior (especially in combination with alcohol) are possible. At high doses: hallucinations, uncontrolled movements (tics), circulatory failure, strokes as well as kidney, liver, heart failure and states of deep unconsciousness. An often underestimated danger is the rise of body temperature up to 41 ºC with life-threatening overheating and dehydration of the body as a consequence.
After coming down: extreme need for sleep, strong feeling of hunger, depressed mood, anxiety, irritability, etc. There is also a risk of unintentionally consuming synthetic impurities. Synthesis impurities occur when the production in the laboratory is not clean. To what extent these impurities and their interaction with amphetamine are harmful to health is not known.
Anamphetamine dependence with psychological symptoms can develop rapidly with regular use. Frequent amphetamine use can lead to deficiency symptoms (calcium deficiency, causes bone and dental problems) and psychological problems such as depression. Intensive use can lead to constant restlessness (but also persistent fatigue), sleep and circulatory disorders, anxiety and paranoia, and even amphetamine psychosis. In addition, high blood pressure, motor disorders, weight loss, skin inflammation ("speed pimples"), stomach problems, abdominal cramps, as well as liver and kidney damage and epileptic seizures are possible. Snorting damages the nasal mucous membranes and nasal septum, and swallowing damages the stomach mucous membranes. Chronic consumption favors cerebral hemorrhages and strokes with sudden paralysis. Chronic consumption may increase the risk of developing Parkinson's dementia later in life.