Substances / Heroin

Heroin (chemical name: diacetylmorphine, DAM) is a semisynthetic substance, belongs to the group of opioids (painkillers) and is produced from raw opium, a substance extracted from opium poppy.

Opioid agonists (formerly: substitutes; drugs used to treat heroin addiction)

Methadone, sustained-release morphine (e.g., Sevre Long®, MST®, Kapanol®), buprenorphine (e.g., Subutex®), levomethadone (L Polamidon®), and diacetylmorphine (Diaphin). These medications are opioids used for stabilization in heroin addiction. For users who are not used to opiates, their use even in small amounts can be life-threatening (severe respiratory depression, risk of suffocation) and the same side effects apply as described below.

Effect

Pain-relieving, balancing, calming, anxiety-relieving and euphoric. The euphoric "flash" at the beginning is followed by a state of well-being and a feeling of indifference, serenity, light-heartedness and self-satisfaction.

Duration

Onset of action

Injected or smoked after a few seconds, snorted after a few minutes
Snorted: after a few minutes

Duration of action
2 - 5 hours, depending on the dose and the quality of the substance.

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Dosage

The dose depends strongly on the preparation or the degree of purity and on the individual tolerance. The lethal dose for individuals without tolerance is about 60 mg of pure heroin.

Forms of appearance‍

Sold as heroin ("street heroin"): white to cream, gray or brownish powder. Sold as tablets or diaphine (diacetylmorphine): Caution, due to pharmacological purity, dosage is approximately 5 times higher than street heroin.

Risks

Slowing of breathing, nausea, vomiting, itching, drop in blood pressure, pulse slowing, pupil constriction and urinary retention may occur. Overdose may result in reduction of respiratory rate or even respiratory arrest with potential brain and organ damage and even death. In the event of an overdose, medical attention must always be sought.

Long-term risks:
With regular use of heroin: confusion, memory lapses, unclear and blurred speech as well as coordination disorders, extreme constipation, reduction of sexual desire. The risk of dependence with psychological and physical symptoms is great. When tolerance has developed and the body is not supplied with the required amount of substance, physical withdrawal symptoms occur 8 - 12 hours after the last heroin intake. Withdrawal symptoms include sweating and chills, eye and nose runny, vomiting, diarrhea, restlessness, irritability, weakness, anxiety, depressive states, painful cramps, insomnia; less commonly, hallucinations, psychotic episodes, and seizures.

Specific risks by form of consumption:
Sniffing: damage to nasal septums and mucous membranes. Risk of hepatitis C infection
Smoking: damage to bronchial tubes and lungs (lungs become gummed up with daily use).
Injections: Venous inflammation and risk of infectious diseases (hepatitis C, HIV/AIDS, fungus). Organ damage can occur due to the impurities in heroin.

Safer Use

Start with a low dose and wait for the effect and tolerance before adding more.
The risk of overdose with life-threatening consequences is particularly high after longer breaks in consumption (no consumption for more than 2 days) and with unexpectedly "pure" substances. Dose significantly lower after a period of abstinence!
If you inject opioids, dose even more carefully, as the range between desired effect (rush) and dangerous overdose is even more difficult to assess. Avoid injecting opioids; the risk of overdose is particularly high. Always use new (clean and sterile) injection material! Never exchange syringes, filters, water, disinfection swabs to avoid transmission of hepatitis and HIV.
Do not rely on dosage information from colleagues who regularly use opioids. Due to habituation or dependence, their doses are significantly higher and can be fatal for new users.
Take longer breaks (at least several days) between consumption.
Refrain from citrus fruits (especially grapefruit) before or during consumption. The combination can lead to an increase in the effect of the opioid and/or respiratory depression.

Mixed use

The simultaneous consumption of depressant substances such as alcohol, ketamine, GHB/GBL, nitrous oxide, benzodiazepines and/or other opioids is dangerous as there is an increased risk of vomiting and unconsciousness. The risk of suffocation is high!
The combination with methoxetamine (MXE, Metha-Keta) increases the opioid effect.
Mixing opioids with DXM is generally not recommended - there is an increased risk of central nervous system disorders as well as heart and respiratory problems. In addition, DXM lowers the individual opioid tolerance, which is why the risk of overdose increases considerably.
The mixed use of opioids with stimulants (such as cocaine, amphetamine, methamphetamine) puts extreme strain on the body and the cardiovascular system. The effects can overlap each other, so that they are subjectively felt to be weaker. If the effect of the stimulants wears off before the opioids, there is a risk of delayed overdose up to respiratory depression.

Substances

3-CMC (Clophedrone)

3-MMC (3-methylmethcathinone)

4-FA

4-MMC (mephedrone)

6-APB

DOM - DOI - DOB

MDA - MDEA - MBDB

Methylone

Synthetic cannabinoids

Extender

No items found.

LSD analogues

LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.

Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.

In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.

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Heroin

Effect

Duration

Dosage

Risks

Medicines

Emergency

Things to know

Current warnings

Advisory service

Downloads

Effect

Duration

Dosage

Risks

Effect

Dosage

Risks

Safer Use

Mixed use

Substances

Sex

Extender

LSD analogues

Medicines

Synthesis impurities

Emergency

Things to know

Current warnings

Advisory service

Downloads