Quick info
Heroin (chemical name: diacetylmorphine, DAM) is a semisynthetic substance, belongs to the group of opioids (painkillers) and is produced from raw opium, a substance extracted from opium poppy.
Opioid agonists (formerly: substitutes; drugs used to treat heroin addiction)
Methadone, sustained-release morphine (e.g., Sevre Long®, MST®, Kapanol®), buprenorphine (e.g., Subutex®), levomethadone (L Polamidon®), and diacetylmorphine (Diaphin). These medications are opioids used for stabilization in heroin addiction. For users who are not used to opiates, their use even in small amounts can be life-threatening (severe respiratory depression, risk of suffocation) and the same side effects apply as described below.
Pain-relieving, balancing, calming, anxiety-relieving and euphoric. The euphoric "flash" at the beginning is followed by a state of well-being and a feeling of indifference, serenity, light-heartedness and self-satisfaction.
Onset of action
Injected or smoked after a few seconds, snorted after a few minutes
Snorted: after a few minutes
Duration of action
2 - 5 hours, depending on the dose and the quality of the substance.
The dose depends strongly on the preparation or the degree of purity and on the individual tolerance. The lethal dose for individuals without tolerance is about 60 mg of pure heroin.
Forms of appearance
Sold as heroin ("street heroin"): white to cream, gray or brownish powder. Sold as tablets or diaphine (diacetylmorphine): Caution, due to pharmacological purity, dosage is approximately 5 times higher than street heroin.
Slowing of breathing, nausea, vomiting, itching, drop in blood pressure, pulse slowing, pupil constriction and urinary retention may occur. Overdose may result in reduction of respiratory rate or even respiratory arrest with potential brain and organ damage and even death. In the event of an overdose, medical attention must always be sought.
Long-term risks:
With regular use of heroin: confusion, memory lapses, unclear and blurred speech as well as coordination disorders, extreme constipation, reduction of sexual desire. The risk of dependence with psychological and physical symptoms is great. When tolerance has developed and the body is not supplied with the required amount of substance, physical withdrawal symptoms occur 8 - 12 hours after the last heroin intake. Withdrawal symptoms include sweating and chills, eye and nose runny, vomiting, diarrhea, restlessness, irritability, weakness, anxiety, depressive states, painful cramps, insomnia; less commonly, hallucinations, psychotic episodes, and seizures.
Specific risks by form of consumption:
Sniffing: damage to nasal septums and mucous membranes. Risk of hepatitis C infection
Smoking: damage to bronchial tubes and lungs (lungs become gummed up with daily use).
Injections: Venous inflammation and risk of infectious diseases (hepatitis C, HIV/AIDS, fungus). Organ damage can occur due to the impurities in heroin.
LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.
Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.
In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.
If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.