Quick info

Hallucinogenic mushrooms with the active ingredient psilocybin grow in the wild and were used by indigenous cultures as a remedy and intoxicant. The best-known varieties are the pointed cone bald man(Psilocybe semilanceata), the "Mexican"(Psilocybe cubensis) and the "Hawaiian"(Panaeolus cyanescens or Copelandia cyanescens). When ingested, psilocybin is converted by the body into the degradation product psilocin, which is responsible for the psychoactive effect of the mushrooms. Psilocin develops its psychoactive effect primarily through the activation of certain serotonin receptors. Clinical research is currently investigating psilocybin as a possible treatment for various psychiatric disorders.

Effect

Dosage

Risks

Safer Use

Mixed use

Sex

Extender

LSD analogues

Synthesis impurities

Contents

Effect

Deep doses: stimulating, slightly euphoric, laughing flash

Medium doses: mildly hallucinogenic and stimulates the imagination

High doses: highly hallucinogenic, very psychedelic. Altered sense of space-time and ego - time expands, the environment is often perceived as dreamlike; visionary immersion in strange worlds, a sense of deep insight into oneself and a feeling of strong connection with nature

Duration

Onset of effect

between 15-60 minutes

Duration of action

3-7 hours, depending on variety and preparation.

Aftereffects

6 hours

EFFECT (of pure psilocybin)

Onset of effect

After 20 - 40 minutes; peak: after 60 - 90 minutes

Duration of action

2-3.5 hours

Appearances

Fresh or dried mushrooms, "Magic Truffles" (Amsterdam); synthetic (pure) psilocybin as a white powder.

Dosage

The active ingredient content is subject to strong fluctuations.

Average dosages of dried* mushrooms:

Pointed cone baldy light: 0.5-0.8 g, medium to heavy 0.8-max. 3 g

"Hawaiian": light 0.3-0.5 g, medium to strong 0.5-max. 2 g

"Mexican": light 0.5-1.5 g, medium to strong 1.5-max. 6 g

*for fresh mushrooms tenfold

Forms of consumption
eaten, drunk in tea, rarely smoked (reduced effect).

Dosage of pure psilocybin:

µg/kg - effect

45 µg/kg - mild to moderate effect

115 µg/kg - medium effect  

215 µg/kg - medium to strong effect

315 µg/kg - very strong effect (doses above 25 mg per total intake should be avoided)

Gender does not affect the dosage, but age does. The older one is, the less unwanted side effects and anxiety occur. This is probably due to the learned better handling of negative feelings as well as the reduction of serotonin receptors, to which psilocybin binds, with increasing age.

For more information on dosage, see our Dosage Magic Mushrooms factsheet.

Risks

Avoid mixed consumption, never consume mushrooms together with alcohol or medication!

Refrain from mixed use with lithium. There is an increased risk of psychosis and stroke.

Do not consume tramadol if you use psychedelic substances. Tramadol lowers the threshold for strokes, while psychedelic substances can trigger them in susceptible individuals.

Cannabis can have unexpected strong effects in combination with psychedelic substances, leading to anxiety, panic attacks and paranoia. Mixed use is discouraged or recommended, dosing cannabis lower than usual and taking long breaks in between.

Safer Use

  • When picking mushrooms in the wild, there is a risk of confusion due to deadly doppelgangers, so always keep a mushroom in case of poisoning! Have your mushrooms identified by a professional inspector. You can also take psychoactive mushrooms back with you after identification in exchange for a signature. You can find the nearest control point and further information under Vapko - Home.
  • Pay attention to the set: consume mushrooms only rested and in good mental and physical condition.
  • Pay attention to the setting: a protected setting is important; mushrooms are not party drugs. Do not use mushrooms alone, but with a companion you trust. Avoid streets and other "dangerous" places, your orientation can be disturbed.
  • Consume a light meal before the trip; eat very little 6 to 8 hours beforehand to avoid nausea and other unpleasant side effects.
  • Use dried mushrooms if possible; wash raw mushrooms well before eating. Chew well!
  • In delicate moments during the trip: let yourself go, do not try to fight the effect of the mushrooms.
  • Avoid mixed consumption, do not consume mushrooms together with alcohol under any circumstances!
  • In case of panic attacks or horror trips: see "In case of emergency".
  • After the trip, allow yourself plenty of rest and recovery, at least the day after, to be able to process the experience.
  • Individuals with high blood pressure, clotting disorders, or other cardiovascular conditions should refrain from consumption due to the potential for serious side effects (heart attack, stroke, embolism, death).
  • Mushrooms or pure psilocybin should not be taken concurrently (on the same day) with psychotropic drugs when taking psychotropic drugs or antimigraine drugs that also act on the serotonin system (antidepressants, opiate pain relievers, triptans), as life-threatening serotonin syndrome may result.
  • People who have first-degree relatives suffering from chronic psychosis should refrain from consumption, as they are at increased risk of triggering psychosis.

Mixed use

Avoid mixed consumption, never consume mushrooms together with alcohol or medication!

Refrain from mixed use with lithium. There is an increased risk of psychosis and stroke.

Do not consume tramadol if you use psychedelic substances. Tramadol lowers the threshold for strokes, while psychedelic substances can trigger them in susceptible individuals.

Cannabis can have unexpected strong effects in combination with psychedelic substances, leading to anxiety, panic attacks and paranoia. Mixed use is discouraged or recommended, dosing cannabis lower than usual and taking long breaks in between.

Cocaine

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Increased risk

We strongly advise against this combination. If possible, stick to a single substance. The health risks are significantly increased—including the risk of overdose, respiratory and circulatory problems, and mental health crises.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Risk

This combination already poses a significant risk. The effects can reinforce each other or change in unpredictable ways. Therefore, use these substances with caution, test new or unfamiliar substances individually first, and keep the doses as low as possible. Allow sufficient time between doses and avoid taking additional doses on a whim. Be aware of the varying durations of action for each substance.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use

Lower risk

Learn about the substances, their effects, how quickly they take effect, and the proper dosage. Get to know each substance on its own first, and see how they affect you and whether they suit you before mixing them. Allow enough time between doses, mix as few substances as possible, and start with low doses.

More about poly-drug use
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Emergency

If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.

Things to know

Current warnings

Advisory service