Substances / 2-MMC (2-Methylmethcathinone)

2-MMC is a synthetic cathinone of the amphetamine group and closely related to mephedrone/4-MMC and is closely related to mephedrone/4-MMC. The substance was developed as a legal alternative after 4-MMC was banned and is one of the little-researched new psychoactive substances. In the meantime, 2-MMC has also been banned in most countries. To date, there is hardly any scientific knowledge about the mechanisms of action, toxicity and long-term effects. The current state of knowledge is mainly based on reports from users. Consumption is therefore associated with a high degree of uncertainty.

Effect

The effect of 2-MMC (2-methylmethcathinone) is described as euphoric, stimulating, activating and slightly empathogenic. In comparison to 3-MMC or 4-MMC 2-MMC is often described as less empathogenic (lower "feeling of connection" as with MDMA), but more stimulating and focusing . The euphoric effect is usually shorter, while the stimulating component is more prominent. 2-MMC is also often described as having a libido-enhancing effect, which is why the substance is also used in a sexual context.

Due to the short duration of action, the craving for 2-MMC and other cathinones is particularly pronounced when consumed nasally. The potential for dependence is significantly higher than with other empathogens such as MDMA or methylone.

Duration

Onset of action
‍Snorted: after 5-15 minutes
Swallowed: after 15 -45 minutes

Duration of action
‍Snorted: 1.5 -3 hours
Swallowed: 2-4 hours

After-effects ("down phase") can last 6-24 hours.

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Dosage

Snuffed‍

Light: 20- 50 mg
Medium: 50- 100 mg
Heavy: 100- 150 mg

Swallowed
Light: 50-100 mg
Medium: 100-150 mg
Strong: 150-250 mg

This dosage information comes from consumer reports and has not been scientifically validated. The individual effect can vary greatly.

Little is known about intravenous, rectal, and inhalation use. These forms of use should be avoided. If you do try any of these forms of use, use as low a dose as possible.

Forms of appearance: White to beige crystalline powder

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Risks

Physical side effects
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Cardiovascular problems: increased pulse, high blood pressure, cardiac arrhythmia, in individual cases circulatory collapse‍
Constriction of the blood vessels: can lead to circulatory disorders (cold hands/feet, tingling, pallor)‍
Dehydration: lack of fluids due to heavy sweating and suppressed thirst‍
Suppression of bodily functions: Hunger, thirst and urge to urinate are often not perceived‍
Nausea, stomach complaints, jaw muscle tension ‍
Sexual dysfunction: Erection problems, orgasm difficulties, temporary loss of libido
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Psychological side effects
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Strong craving (desire to refill): frequent refills → high risk of losing control
Paranoid thoughts and psychotic phases: especially with high doses or lack of sleep
Anxiety and inner restlessness
Depressive moods after consumption ("crash")
Listlessness and emotional emptiness in the days following use
Irritability, mood swings and concentration problems

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Long-term risks

Possible neuro- and cardiotoxic effects: Evidence of neurotoxic and cardiotoxic potential with repeated or high consumption
As with other cathinones, a high psychological dependency potential is likely.

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Safer Use

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About cathinones there is little knowledge. You are therefore exposing yourself to unknown risks.

Many fake cathinone samples are tested in the drug checking offers. Have the substance analyzed in a drug check. If this is not possible and you still want to consume it, then try small amounts to get to the desired dose.

If you decide to use, be as informed as possible about the specific substance and the appropriate dosage - pay attention to your basic mood and the environment in which you use (set and setting), even with NPS.

Do not purchase any product with a fancy name without a declaration of ingredients.

Inform your friends about what and how much you have consumed.

Refrain from mixed consumption, as interactions are dangerous and unexplored.

People with high blood pressure, heart problems, hyperthyroidism, liver and kidney disease, or circulatory problems should not take New Psychoactive Substances.
Consume orally rather than nasally to reduce the urge to take more (note differences in dosage and onset of effect).

You can find more safer use messages here: Safer Use

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Mixed use

Mixed use with other substances can significantly increase the risk. Combinations with are particularly dangerous:

other stimulants (e.g. amphetamine, cocaine, MDMA, 4-FA, methamphetamine, methylone): greatly increased circulatory stress
MAO inhibitors or SSRIs: risk of life-threatening serotonin syndrome
Alcohol or benzodiazepines(e.g. diazepam, alprazolam): additional strain on the cardiovascular system and liver
Ketamine or GHB/GBL: unpredictable intensification of effects and loss of control‍
Tramadol: increased risk of seizures and strokes‍
25x-NBOMe or 25x-NBOH (highly potent, serotonergic hallucinogens): strong overstimulation with panic attacks, seizures, high blood pressure and vasoconstriction, in severe cases heart failure possible.

Other potentially harmful combinations cannot be ruled out, as there is no scientifically sound information on interactions with cathinones.‍

Substances

3-CMC - 4-CMC

3-MMC (3-methylmethcathinone)

4-FA

4-MMC (mephedrone)

6-APB

DOM - DOI - DOB - DOC

MDA - MDEA - MBDB

Methylone

Synthetic cannabinoids

Sex

Like other cathinones, 2-MMC can have a sexually stimulating and disinhibiting effect. Many users report increased libido, heightened sensitivity and a desire for physical closeness, although these effects vary greatly from person to person.

Compared to 3-MMC and 4-MMC, 2-MMC is usually described as less empathogenic and emotionally connecting, but more physically stimulating and drive-boosting. While 3-MMC and 4-MMC more often evoke a feeling of tenderness or emotional openness (similar to MDMA), 2-MMC tends to focus more on direct sexual arousal and activation.

However, higher doses or prolonged use can lead to erectile dysfunction, orgasm difficulties or a lack of sexual climax - an effect that is also known from other stimulating substances. After the effect wears off, some people report reduced libido, irritability or exhaustion.

Sex on mind-altering substances can have an intense effect, but can also involve additional risks. You can find more information on safer sex and substances here.

Extender

Since 2023, synthetic cathinones such as 2-MMC and 3-MMC have been increasingly circulating in the party scene again. An increasing number of samples containing alleged 3-MMC or 2-MMC are currently being handed in for drug checking in Switzerland.

The analysis results show that up to 75% of these samples do not contain the expected active substance. Often unexplored or cheaply produced new psychoactive substances (NPS) such as 3-CMC,4-CMC, 2-MEC or dimethylpentylone (N,N-dimethylpentylone) are sold as "2-MMC" or "3-MMC".

In addition to such misdeclarations, many samples also contain synthesis by-products and residues from the manufacturing process . These are caused by inadequate purification or improper synthesis steps and can pose a health risk.

No items found.

LSD analogues

LSD analogues are substances that are chemically very similar to LSD and can have comparable effects. Some of them have been known for a long time (e.g. ALD52, ETH-LAD, AL-LAD, PRO-LAD etc.) and have been studied pharmacologically as well as psychopharmacologically, at least in part. Others are newer "creations" (e.g. the derivatives 1P-LSD,1B-LSD, 1cP-LSD, 1V-LSDetc.), for which only few or no data are available. Certain LSD analogues can (still) be legally produced, traded and consumed in some countries, which is the main reason for their distribution.

Most LSD analogues are naturally different from LSD in their effect and/or potency (e.g. ETH-LAD, AL-LAD, LSZ etc.). In contrast, the so-called 1-acylated LSD compounds (e.g. 1P-LSD, 1V-LSD, 1B-LSD, ALD-52, etc.) are presumed, on the basis of pharmacological studies, to convert into LSD in the body (they function as so-called prodrugs) and thus have a comparable psychoactive effect to LSD.

In the case of prodrugs of LSD and LSD analogues, it has not been conclusively clarified whether, in addition to their psychoactive effect, they can produce other pharmacological effects. How potent these prodrugs are compared to the resulting substance (e.g., 1P-LSD to LSD), and to what extent a delay in onset of action occurs in each case, may be substance-dependent and cannot be generalized. Therefore, it is important to approach the dose/effect carefully to avoid overdoses.

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Medicines

Nitazene

Pregabalin

Anabolic Androgen Steroids (AAS)

Modafinil

Dexamphetamine and Adderall

Diacetylmorphine (Diaphin®)

Buprenorphine (Subutex®)

Oxycodone

Flualprazolam

Etizolam

Lorazepam (Temesta®)

Midazolam (Dormicum®)

Oxazepam (Seresta®)

Flunitrazepam (Rohypnol®)

Diazepam (Valium®)

Fentanyl

Morphine / morphine

Tilidine

Tramadol

Dextromethorphan or Bexin®

Neuroleptics

Viagra®

Alprazolam (Xanax®)

Methylphenidate (Ritalin®)

Codeine

Synthesis impurities

No items found.

Emergency

If you or someone else needs urgent help after taking drugs or alcohol, call an ambulance on 144. Tell the emergency responders everything you know.
It could save lives.

Call 144